Gpiib

Pedovex is an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) binding to its receptor and of the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex.
➢The advantage of Clopidogrel over aspirin is its selectivity of action.
➢By this mode of action it also inhibits the expression of GPIIb/llla receptors needed for the formation of fibrin bridges which link the platelets.
➢Unlike aspirin, Clopidogrel does not inhibit cyclooxygenase, which means there is no reduction in synthesis of prostaglandins which protect the Gl tract. Hence, the incidence of Gl side effects is reduced with clopidogrel compared with aspirin.

INDICATIONS AND DOSAGE
1-Recent MI, Recent Stroke, or Established Peripheral Arterial Disease
The recommended daily dose of PEDOVEX is 75 mg once daily.

2-Acute Coronary Syndrome
-For patients with non-ST-segment elevation acute coronary syndrome (unstable angina/non-Q-wave MI), PEDOVEX should be initiated with a single 300 mg loading dose and then continued at 75 mg once daily. Aspirin (75 mg-325 mg once daily) should be initiated and continued in combination with PEDOVEX.

-For patients with ST-segment elevation acute myocardial infarction, the recommended dose of Clopidogril is 75 mg once daily, administered in combination with aspirin, with or without thrombolytics. PEDOVEX may be initiated with or without a loading dose.


PEDOVEX
•Pedovex is a high quality clopidogrel
•Pedovex is bioequivalent to the Originator
•Pedovex is a Tabuk product, thus manufactured under European standard since Tabuk hold EGMP
•Pedovex offers the patient the high Efficacy, The high quality , yet affordable price
This Application Describe All Details of Pedovex